Burroughs (7-1, 5-0 in league) is riding a five-game winning streak.
Burroughs senior running back Joe Wiggan scored three touchdowns — two in the opening half, and finished with a game-best 237 yards. Wiggan carried the ball 35 times and seemed to get stronger as the night wore on.
"I take a lot of hits, but that doesn't bother me," said Wiggan, who moved into second for yardage in a season with 1,379 yards, surpassing Thomas Kyle's 1,364 set last season.
At 5-feet-10, 180 pounds, Wiggan likes running in traffic and is tough and elusive.
"When I run, I always keep my head down, lower my shoulder pads and keep my feet moving," he said. "I'm always driving for extra yards."
Wiggan's 25-yard scoring burst with 2:16 left in the game gave the Indians a 15-point lead.
"We're not looking past any team," Wiggan said. "We're trying to knock on one door at a time. I just think about the next game, and not look ahead."
Burroughs went up, 7-0, with 7:59 left in the opening quarter when senior linebacker Keith Recchia stripped Arcadia junior running back Troy Ahmaz of the ball and raced 60 yards for the touchdown.
Wiggan, who came into the game with 18 rushing touchdowns, scored from seven yards out and 4:36 showing on the clock, as the Indians raced out to a 14-0 lead.
The Apaches (4-4, 3-2) trimmed the lead to 14-6 when quarterback Nick Ponce hit junior wide receiver Kevin Walker on a 50-yard strike and 2:10 left in the first quarter.
Burroughs took a 21-6 lead into the locker room after Wiggan scored on a 14-yard dash.