Here's a look at the other three games:
The Indians (19-7) tied Crescenta Valley for the Pacific League title, but enter the playoffs as the league's No. 1 seed after having a higher run differential against the Falcons.
They will take on the winner of Tuesday's Division III wild-card game between St. Lucy's and Fillmore at 3:15 p.m. Thursday at Olive Park.
First-year Indians Coach Doug Nicol said his team is ready to start the playoffs on a positive note.
"I'm excited about the playoffs, and I know the girls are excited," Nicol said. "We think that we have the talent to make some noise in the playoffs. We are an invigorated team right now and we will be ready to go [Thursday]."
Burroughs — which also won a league crown in 2010 — is fresh of a 5-3 win last week against cross-town rival Burbank.
The Indians come into the first-round contest after winning nine of their final 10 games of the regular season.
Burroughs has a dangerous group of hitters, including six who are batting .400 or better. The team has been led by junior catcher Shannon Trujillo, who is hitting .430 with eight home runs, 37 hits, 34 runs batted in and 33 runs scored.
The team also has accomplished hitters in seniors Hailee White and Taylor Buliavac, along with junior Haley Schulman.
In the circle, the Indians have been paced by junior pitcher Heather Haynes, who is 9-2 with a 2.17 earned-run average and 88 strikeouts.
The Guards (18-5) received the No. 2 seeding in the division after rolling to an easy title in the Santa Cruz League. It was the program's second straight championship.
The Guards will host the winner of Tuesday's wild-card game between Public Safety Academy and Maricopa in a Division VII game at 3:15 p.m. Thursday at Gross Park.